A comprehensive program for cervical cancer detection and management.
Mortality from cancer of the uterus in Canada and its relationship to screening for cancer of the cervix. Atlanta, Ga: American Cancer Society, 2008.
5 for all comparison pairs).Ĭonclusion: In this study, 3.0-T MR imaging was characterized by high diagnostic accuracy in the presurgical evaluation of patients with cervical carcinoma, although 3.0-T imaging was not significantly superior to 1.5-T imaging. Neither radiologist noted significant differences between values obtained with 3.0-T imaging and those obtained with 1.5-T imaging ( P >. Corresponding values for lymph node metastases were (a) 57% for both 3.0- and 1.5-T imaging, (b) 83% for 3.0-T imaging and 88% for 1.5-T imaging, and (c) 0.72 for 3.0-T imaging and 0.78 for 1.5-T imaging, respectively. Corresponding values for vaginal invasion were (a) 67% for both 3.0- and 1.5-T imaging, (b) 68% for 3.0-T imaging and 72% for 1.5-T imaging, and (c) 0.62 for 3.0-T imaging and 0.67 for 1.5-T imaging, respectively. Sensitivity, specificity, and area under the receiver operating characteristic curve for radiologist 1 in the evaluation of parametrial invasion were (a) 75% for both 3.0- and 1.5-T imaging, (b) 70% for both 3.0- and 1.5-T imaging, and (c) 0.82 for 3.0-T imaging and 0.85 for 1.5-T imaging, respectively. Interobserver agreement between the two radiologists for local-regional staging was good or excellent (κ = 0.65–0.89). There were no significant differences in terms of the degree of susceptibility artifacts. Image homogeneity at 3.0-T imaging was significantly inferior to that at 1.5-T imaging ( P =. Results: Mean tumor signal-to-noise ratios, mean cervical stroma signal-to-noise ratios, and mean tumor-to–cervical stroma contrast-to-noise ratios at 3.0-T imaging were significantly higher than those at 1.5-T imaging ( P = 9.1 × 10 −6, P = 1.8 × 10 −6, and P =. MR findings were compared with surgicopathologic findings. Two radiologists independently evaluated images in terms of local-regional staging. Quantitative and qualitative analyses were performed. Thirty-one consecutive patients (age range, 27–71 years mean age, 51.1 years) underwent 3.0- and 1.5-T MR imaging. Materials and Methods: Institutional review board approval and informed consent were obtained.
Purpose: To prospectively evaluate the efficacy of 3.0-T magnetic resonance (MR) imaging in the preoperative staging of cervical carcinoma compared with that at 1.5-T imaging, with surgery and pathologic analysis as the reference standards.
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